Partner disability and suffering affect older adult caregivers’ psychological and physical health; but how can support and interpersonal emotion regulation processes protect caregivers and their partners? Our goal is to answer this research question, seek ways to minimize the negative consequences of caregiving, and improve the quality of life and health of caregivers and their partners. To achieve this, the Yale Social Gerontology and Health lab implements cutting edge mixed- methods approaches such as psychophysiological, behavioral, genetic, and linguistic analyses. Minimizing the negative health effects of caregiving is a growing public health issue, given that the 65+ age group is expected to double to 70 million in 2030. The Yale Social Gerontology and Health lab’s research aims to address the mental and physical health needs of older adult caregivers and their care- recipients.